I need Solution for Large Table

Hi All,<o:p></o:p>

I have a huge table near about 117088326 Records and the space usage is as below<o:p></o:p>

Data: 57GB 
Index: 84GB<o:p></o:p>

Obviously the query which I execute against it will be somewhat solve because of large table 
can anyone suggest solution on it <o:p></o:p>

Note: I am using SQL Server 2008 r2 Standard Edition (It means no table Partitioning)<o:p></o:p>